منابع مشابه
Anesthetic Pharmacology Preclinical Pharmacology
Daniel I. Sessler, MD† BACKGROUND: In previous studies, we showed that failure to respond to automated responsiveness monitor (ARM) precedes potentially serious sedationrelated adversities associated with loss of responsiveness, and that the ARM was not susceptible to false-positive responses. It remains unknown, however, whether loss and return of response to the ARM occur at similar sedation ...
متن کاملAnesthetic Pharmacology
Jürgen Sandkühler, MD, PhD§ BACKGROUND: Xenon’s (Xe) mechanisms for producing anesthesia and analgesia are not fully understood. We tested the effect of Xe equilibrated in a lipid formulation or normal saline on spinal C-fiber-evoked potentials and on the induction of synaptic long-term potentiation (LTP). METHODS: C-fiber-evoked field potentials were recorded in the superficial lumbar spinal c...
متن کاملAnesthetic Pharmacology International Society for Anaesthetic Pharmacology
We hypothesized that N-methyl-d-aspartate (NMDA) receptors mediate some or all of the capacity of inhaled anesthetics to prevent movement in the face of noxious stimulation, and that this capacity to prevent movement correlates directly with the in vitro capacity of such anesthetics to block the NMDA receptor. To test this hypothesis, we measured the effect of IV infusion of the NMDA blockers d...
متن کاملEssentials of local anesthetic pharmacology.
It is impossible to provide effective dental care without the use of local anesthetics. This drug class has an impressive history of safety and efficacy, but all local anesthetics have the potential to produce significant toxicity if used carelessly. The purpose of this review is to update the practitioner on issues regarding the basic pharmacology and clinical use of local anesthetic formulati...
متن کاملThe Pharmacology Of Intravenous Anesthetic Induction Agents: A Primer
their optimal clinical utilization. History and Principles Whereas inhaled anesthetics are useful for the induction of anesthesia, particularly in the absence of IV access as occurs commonly in pediatric anesthesia, IV anesthetics have become the primary agents for the induction of general anesthesia. The development of IV anesthetics followed the late 19th-century introduction of hollow needle...
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ژورنال
عنوان ژورنال: Anesthesiology
سال: 2012
ISSN: 0003-3022
DOI: 10.1097/aln.0b013e318260cc1f